Prenatal Testing

Through prenatal testing you can learn much before your child is even born. While it can provide simple information such as whether you will have a boy or girl, prenatal testing can also help diagnose genetic abnormalities that could impact the mental and physical development of your child. AneuVysion is not intended for use as a stand alone test, but should be used in a manner consistent with professional standards of practice. AneuVysion is designed for women with presumed high risk pregnancies. AneuVysion is available through prescription only and patients should consult with their physician to learn more. Consult the Warnings & Limitations section of this website for important information.

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What kind of technology does AneuVysion use?
The AneuVysion test uses Fluorescent In situ Hybridization (FISH) technology to attach colored DNA probes to specific chromosomes in the fetal cells. These colored probes are added to some of the cells obtained from an amniocentesis. Unlike karyotyping, this test doesn't require growth of the cells in a laboratory incubator. Thus, cells can be analyzed within hours after the DNA probes are added.

What kind of technology does AneuVysion use?

The AneuVysion test uses Fluorescent In situ Hybridization (FISH) technology to attach colored DNA probes to specific chromosomes in the fetal cells. These colored probes are added to some of the cells obtained from an amniocentesis. Unlike karyotyping, this test doesn't require growth of the cells in a laboratory incubator. Thus, cells can be analyzed within hours after the DNA probes are added.

Fluorescent in situ hybridization (FISH) technology
*Fluorescence in situ* hybridization (FISH) is a type of hybridization in which a DNA "probe" is labeled with fluorescent molecules so that it can be seen with a microscope**. The word "in situ" means that the hybridization occurs "in place", in this case, within the nucleus of specimen cells that have been fixed to a microscope slide. To conduct a FISH analysis, one warms fixed cells mounted on a microscope slide to unwind their chromosomal DNA and allow access of the DNA probe. After adding the probe, the specimen cells are then cooled to allow the DNA probe to hybridize with its complementary target DNA. Once the probe is hybridized, the fluorescent molecules on the probe will show precisely where their target DNA lies along a chromosome. Depending upon the design of the probe DNA, one can detect many types of genetic changes. Please see the AneuVysion video for more information.

Fluorescent in situ hybridization (FISH) technology

Fluorescence in situ hybridization (FISH) is a type of hybridization in which a DNA "probe" is labeled with fluorescent molecules so that it can be seen with a microscope. The word "in situ" means that the hybridization occurs "in place", in this case, within the nucleus of specimen cells that have been fixed to a microscope slide.

To conduct a FISH analysis, one warms fixed cells mounted on a microscope slide to unwind their chromosomal DNA and allow access of the DNA probe. After adding the probe, the specimen cells are then cooled to allow the DNA probe to hybridize with its complementary target DNA. Once the probe is hybridized, the fluorescent molecules on the probe will show precisely where their target DNA lies along a chromosome. Depending upon the design of the probe DNA, one can detect many types of genetic changes.

Please see the AneuVysion video for more information.

Multicolor DNA Probe Kit

Prenatal Testing